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The High-Energy Ion Telescope (HIT) for the Interstellar Mapping And Acceleration Probe (IMAP) Mission.

Space science reviews·2026

Significant hindlimb static weight-bearing asymmetry persists for 40-weeks in a longitudinal study in two widely used rat models of surgically induced osteoarthritis knee pain.

Frontiers in pharmacology·2025

The angiotensin II type 2 receptor antagonists, PD123,319 ((S-( +)-1-[(4-(dimethylamino)-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid), EMA300 (5-(2,2-diphenylacetyl)-4-[(4-methoxy-3-methylphenyl)methyl]-1,4,6,7-tetrahydroimidazo[4,5-c]pyridine-6-carboxylic acid) and EMA401 ((3S)-5-(benzyloxy)-2-(2,2-diphenylacetyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid), evoke pain relief in a varicella zoster virus-induced rat model of neuropathic pain.

Inflammopharmacology·2025

J-2156, a small molecule somatostatin type 4 receptor agonist, alleviated hindpaw hypersensitivity in the streptozotocin-induced rat model of painful diabetic neuropathy but with a 2-fold decrease in potency at an advanced stage in the model, mimicking morphine.

Frontiers in pharmacology·2024

Prostate cancer induced bone pain: pathobiology, current treatments and pain responses from recent clinical trials.

Discover oncology·2022

Small-molecule disruption of the TRAF6-Ubc13 protein-protein interaction: targeting noncanonical ubiquitin signaling in inflammation and cancer.

Biochemical pharmacology·2026

Targeting PKM2 by (+)-homocrepidine A restrains glycolytic reprogramming and reshapes macrophage fate to alleviate acute lung injury.

Biochemical pharmacology·2026

Thumpd1 preserves osteogenic TGF-β signaling by promoting USP4-dependent deubiquitination and stabilization of TGF-βRII.

Biochemical pharmacology·2026

Calcium oxalate-induced renal epithelial cell injury is mediated by receptor-interacting serine/threonine kinase 2 (RIPK2).

Biochemical pharmacology·2026

Integrin αVβ3-mediated focal adhesion signaling promotes fibroblast activation during renal fibrosis.

Biochemical pharmacology·2026

Genistein inhibits colorectal cancer progression via regulating the LINC00355/miR-150/SGK1 axis and downstream EGFR/PI3K/AKT and MAPK signaling pathways.

Biochemical pharmacology·2026

Colorimetric detection of H2O2 based on the synergistic catalytic enhancement effect of Fe3O4@NH2-MIL-88B.

Analytical methods : advancing methods and applications·2026

Circularly polarized electroluminescence from topologically chiral [2]catenane-based neutral radicals with tunable deep-red emission.

Nature communications·2026

Synthesis of Chiral-at-Sulfur(VI) Sulfonimidamide Brønsted Acids.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026

Deaminative C(sp3)-C(sp2) and C(sp3)-S coupling of alkylamines.

Chemical communications (Cambridge, England)·2026

TiO2‑Mediated Enamine Radical Cation Cycloadditions: Divergent [4 + 2] and [2 + 2] Reactivity.

Precision chemistry·2026

Oxidative Arene Ring-Opening of Benzylic Alcohols.

JACS Au·2026

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An NLRP3 inflammasome inhibitor evoked dose-dependent anti-allodynia in the hindpaws of a rat model of chemotherapy-induced peripheral neuropathy.

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Significant hindlimb static weight-bearing asymmetry persists for 40-weeks in a longitudinal study in two widely used rat models of surgically induced osteoarthritis knee pain.

J-2156, a small molecule somatostatin type 4 receptor agonist, alleviated hindpaw hypersensitivity in the streptozotocin-induced rat model of painful diabetic neuropathy but with a 2-fold decrease in potency at an advanced stage in the model, mimicking morphine.

Prostate cancer induced bone pain: pathobiology, current treatments and pain responses from recent clinical trials.

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Calcium oxalate-induced renal epithelial cell injury is mediated by receptor-interacting serine/threonine kinase 2 (RIPK2).

Integrin αVβ3-mediated focal adhesion signaling promotes fibroblast activation during renal fibrosis.

Genistein inhibits colorectal cancer progression via regulating the LINC00355/miR-150/SGK1 axis and downstream EGFR/PI3K/AKT and MAPK signaling pathways.

Colorimetric detection of H2O2 based on the synergistic catalytic enhancement effect of Fe3O4@NH2-MIL-88B.

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Inhibitory effect of superoxide-generating quinones on superoxide dismutase

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