Related Experiment Video
Updated: May 5, 2026

05:45
Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
Published on: April 26, 2019
13.4K
Abnormal rectoanal function in children recovered from chronic constipation and encopresis
Gastroenterology
|December 1, 1984
Summary
Abnormal anal sphincter function persists years after constipation and encopresis treatment. This impaired relaxation and hypotonia increase the risk of recurrence in recovered children.
Area of Science:
- Pediatric Gastroenterology
- Colorectal Surgery
- Physiology
Background:
- Chronic constipation and encopresis in children can be linked to abnormal anal sphincter function.
- Long-term functional outcomes after treatment are not well-established.
Purpose of the Study:
- To investigate persistent anal sphincter dysfunction in children years after resolution of chronic constipation and encopresis.
- To assess if abnormal anorectal manometry findings predict long-term outcomes.
Main Methods:
- Anorectal manometry was performed on healthy controls, children with constipation, and children with constipation and encopresis.
- Measurements included anal resting tone, anal pull-through pressure, and rectosphincteric reflex response to rectal distention.
- Follow-up manometry was conducted 2.5-4 years after treatment initiation in the constipation and encopresis group.
Main Results:
- Children with constipation and encopresis exhibited lower anal resting tone, anal pull-through pressure, and impaired rectosphincteric reflex relaxation compared to controls.
- These abnormalities persisted significantly even years after treatment initiation, in both recovered and non-recovered patients.
- Rectosphincteric reflex threshold was comparable across groups.
Conclusions:
- Decreased internal anal sphincter relaxation and anal canal hypotonia are likely underlying causes of chronic constipation and encopresis in children.
- Abnormal anorectal function persists long-term, placing recovered patients at risk for recurrence.
Related Concept Videos
Chronic Bowel Disorders: Introduction
906
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
906
Drugs for Treatment of Constipation-Predominant IBS
1.5K
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
1.5K
Feces Formation and Defecation
6.5K
After spending 3 to 10 hours in the large intestine, chyme loses a lot of water and becomes feces, the final product of digestion. Feces consist of undigested dietary fiber such as cellulose, mucus, sloughed-off epithelial cells, and microbes. The descending and sigmoid colon stores feces and uses haustral contractions to dry it out but retains enough water to give it a semi-solid texture.
The mass peristalsis then pushes the feces into the rectum, which stretches the rectal walls to activate...
The mass peristalsis then pushes the feces into the rectum, which stretches the rectal walls to activate...
6.5K
Assessment of the Rectum and Anus
2.1K
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
2.1K
Inflammatory Bowel Disease V: Surgical Management
926
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
926
Psychosexual Stages of Personality: Anal
5.7K
Sigmund Freud's theory of psychosexual development describes the anal stage as occurring between 18 months and three years of age. During this period, children derive pleasure from controlling and releasing their bowel movements. However, they quickly learn that societal expectations impose restrictions on when and where this can happen. This stage marks a critical point where children begin to develop a sense of control and mastery over their bodily functions, as well as their broader...
5.7K

