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[Transient reduced adrenal gland function following large vascular surgical interventions]
Zentralblatt Fur Chirurgie
|January 1, 1984
Summary
Aorto-femoral bypass surgery can temporarily lower serum corticoids, potentially causing adrenal insufficiency in some patients. This may be due to adrenal hemorrhage from heparinization during the procedure.
Area of Science:
- Endocrinology
- Vascular Surgery
- Surgical Complications
Context:
- Aorto-femoral bypass operations are common vascular procedures.
- Postoperative complications require careful monitoring.
- Adrenal function can be affected by surgical stress and medications.
Purpose:
- To investigate the impact of aorto-femoral bypass surgery on total serum corticoid levels.
- To compare postoperative corticoid levels with a control group undergoing major abdominal surgery.
- To assess adrenal function using ACTH stimulation tests in affected patients.
Summary:
- 48 patients undergoing aorto-femoral bypass had pre- and postoperative serum corticoid measurements.
- Twelve patients showed decreased corticoid levels, with six exhibiting signs of relative adrenal insufficiency.
- ACTH stimulation tests confirmed reduced adrenal response, potentially linked to adrenal hemorrhage from heparinization.
Impact:
- Highlights a potential risk of temporary adrenal insufficiency following aorto-femoral bypass.
- Suggests careful monitoring of corticoid levels and adrenal function in these patients.
- Identifies systemic heparinization and potential adrenal hemorrhage as causative factors.