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Modulation of mast cell cAMP levels. A regulatory function of calmodulin
Abstract:
Modulations of cyclic AMP (cAMP) levels and secretory capacity in both immunological and non-immunological stimulation of rat mast cells are influenced by the calmodulin inhibitor trifluoperazine. A model of a calcium-dependent joint regulation of cyclic nucleotide turnover in these two types of mast cell stimulation is presented.