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[Experimental venous thrombosis in guinea pigs: effect of heparin and drugs affecting platelet function (author's
Abstract:
Thrombosis was induced in the jugular vein of guinea pigs by damage of the epithelium with a sclerosing solution. The effect of heparin, Dextran 70, acetylsalicylic acid, dypriridamole and phenilbutazone in preventing the development of the thrombus was investigated. Only heparin in high doses showed this effect.