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Related Experiment Videos

Pharyngoconjunctival fever.

N Giladi, J Herman

    Archives of Disease in Childhood
    |December 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Adenovirus type 3 caused an illness in infants and toddlers, characterized by fever, conjunctivitis, and a unique migratory palpebral erythema. This outbreak highlights the importance of identifying viral causes in pediatric infections.

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    Area of Science:

    • Pediatric Infectious Diseases
    • Virology
    • Epidemiology

    Background:

    • Outbreaks of infectious diseases in childcare settings pose significant public health challenges.
    • Early identification of causative agents is crucial for effective management and prevention.

    Purpose of the Study:

    • To identify the causative agent of an unusual illness affecting infants and toddlers in multiple day nurseries.
    • To characterize the clinical presentation of the illness, including a novel sign.

    Main Methods:

    • Clinical observation of affected children across four day nurseries.
    • Viral isolation and identification from nasopharyngeal swabs of ill children.

    Main Results:

    • Sixteen infants and toddlers presented with fever, conjunctivitis, respiratory infection, lymphadenopathy, otitis media, and migratory palpebral erythema.

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  • Adenovirus type 3 was identified as the etiological agent in the initial cases.

    • Conclusions:

    • Adenovirus type 3 can cause a distinct clinical syndrome in young children.
    • Migratory palpebral erythema may be a characteristic sign of Adenovirus type 3 infection in this age group.