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Related Experiment Videos

Urinary calculi in children.

E Freundlich, K Saab, W Bitterman

    Urology
    |November 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Urinary calculi (kidney stones) occur frequently in Oriental Jewish and Arab children in Western Galilee. A high family incidence suggests hereditary factors are important in this population.

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    Area of Science:

    • Pediatric Nephrology
    • Medical Genetics
    • Epidemiology

    Background:

    • Urinary calculi (kidney stones) exhibit varying prevalence across different ethnic groups.
    • Previous studies indicated higher rates in Oriental Jewish and Arab children compared to Ashkenazic European children in the Western Galilee region.
    • The etiology of idiopathic urinary calculi remains incompletely understood.

    Purpose of the Study:

    • To investigate the incidence and familial aggregation of urinary calculi in children from the Western Galilee region.
    • To explore potential hereditary factors contributing to urinary calculi in a high-incidence population.

    Main Methods:

    • Retrospective analysis of 47 pediatric urinary calculi cases over 13 years.
    • Epidemiological data collection on affected children and their family members.

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  • Comparison of incidence rates across different ethnic groups.

    • Main Results:

    • High incidence of urinary calculi observed in Oriental Jewish (0.29/1,000) and Arab children (0.26/1,000).
    • Low incidence noted in Ashkenazic European children (0.04/1,000).
    • Significant familial aggregation: 21 out of 47 cases had affected family members (up to second cousins).

    Conclusions:

    • Hereditary factors likely play a significant role in the etiology of urinary calculi in this high-incidence population.
    • The study highlights the importance of family history in assessing risk for urinary calculi.
    • Further research into genetic predispositions is warranted.