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Long-term Blood Pressure Measurement in Freely Moving Mice Using Telemetry
Published on: May 17, 2016
Blood-pressure and its correlates in urban and tribal Africa
Abstract:
Blood-pressure and associated factors were compared in tribal and urban Xhosa people of Southern Africa. In the urban group blood-pressures were high and rose significantly with age whereas in the tribal group they were low and rose little with age. Indices of obesity including weight, skin-fold thickness, and ponderal index were significantly greater in urban dwellers and correlated strongly with arterial pressure. Dietary sodium and urine-sodium/creatinine ratio were significantly higher in the urban people, but there was no within-population relationship between either dietary sodium or urine-sodium/creatinine ratio and blood-pressure. Plasma-noradrenaline, an index of sympathetic activity, was similar in both populations, as was plasma-renin activity. Low plasma-renin was common and may be genetically determined. Diet and obesity may contribute to the rise in arterial pressure that is a consequence of urbanisation.
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The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the diastolic...
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