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Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
08:35

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

[Modern treatment of hypertension in older patients (author's transl)]

W Klein

    Aktuelle Gerontologie
    |January 1, 1980
    PubMed

    Insights

    Hypertension management in older adults requires careful consideration of aortic stiffness and co-existing conditions. Gradual blood pressure reduction and initial use of diuretics or vasodilators are recommended for effective treatment.

    Area of Science:

    • Gerontology
    • Cardiovascular Medicine
    • Pharmacology

    Context:

    • Aging population presents unique challenges in hypertension management.
    • Distinguishing arteriosclerotic hypertension from true hypertension in the elderly is crucial.
    • Older patients often have long-standing hypertension with increased peripheral resistance and low cardiac output.

    Purpose:

    • To outline therapeutic strategies for hypertension in older individuals.
    • To emphasize the need for cautious blood pressure management in elderly patients with comorbidities.
    • To identify appropriate first-line pharmacologic agents for geriatric hypertension.

    Summary:

    • Therapy for hypertension in older patients generally mirrors that in younger individuals but necessitates slower blood pressure reduction.
    • Diuretics or vasodilating agents are often the preferred initial choice due to typical physiological changes in older hypertensive patients.
    • Beta-blockers and ganglion-blocking agents require cautious administration in this demographic.
    • Non-pharmacological interventions like salt restriction are valuable for blood pressure control.

    Impact:

    • Informs clinical practice for managing hypertension in the elderly.
    • Highlights the importance of individualized treatment plans considering comorbidities.
    • Contributes to improved cardiovascular outcomes in aging populations through optimized hypertension management.

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