Pimozide as an adjuvant to maintenance therapy in chronic schizophrenia

An open, 12-week study of pimozide (8 mg per day) used concurrently with previous maintenance therapy was carried out to investigate improvements in the social behaviour of 20 chronic schizophrenics. Ward behaviour, work habits and mental status all showed statistically significant improvement after 8 weeks of treatment. The incidence of side-effects was low.