[The biochemical basis of gerontotherapy (author's transl)]

In animal experiments biochemical changes in the aging brain can be shown to occur in the neurotransmitter systems, in cerebral blood flow and energy metabolism, and as lipofuscin accumulation. Neither the causes nor the functional consequences of these changes are well understood. However, analysis of the data is pointing the way to a rational therapy of geriatric disorders based on new drugs with relevant pharmacological effects.