Clinicopathologic and histochemical study of ovarian clear cell carcinoma

Thirteen case reports of mesonephroid clear cell carcinoma of the ovary were analyzed and nine of the tumors were studied histochemically. No disorders were found in the hormonal balance of patients. The tumors produced few symptoms, indicating late discovery and bad prognosis. Histopathologically, the tumors were subdivided into the following groups: glandular, papillary, mixed-type and anaplastic. All of them contained glycogen and neutral mucins; acid mucins were found mainly in glandular tumors, which contained more sulfomucins than carboxymucins. Generally, the most active glandular tumors did not produce sialomucins. No clear correlations between prognosis and clinical pictures, morphology or constitution of cell excretions were found.