Related Experiment Video
Updated: Aug 19, 2026

Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism
Published on: February 14, 2022
[Constant positive pressure mechanical ventilation (CPPV) and intermittent demand ventilation (IMV)]
Abstract:
The application and regulation of CPPV and IMV are reviewed in the light of the pathophysiology of acute pulmonary failure and the effects of these ventilatory techniques. Although a number of these events and their therapeutic implications are now well understood, several questions concerning the importance and mechanisms of secondary effects remain to be answered. Both CPPV and IMV have specific indications and advantages over other ventilatory in selected cases.
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