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Updated: Aug 18, 2026

Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
Squamous cell carcinoma of the vulva and Fanconi anemia
Abstract:
Malignant neoplasia frequently occurs with Fanconi anemia. Generally this represents hematologic disease; however, solid tumors may also appear. The woman described here developed squamous cell carcinoma of the vulva at age 28, and is the third such case in a patient with Fanconi anemia that has been reported. It is a diagnosis to be considered for the young patient with this type of carcinoma. Increased chromosomal breakage in this syndrome may be important in the pathogenesis of these neoplastic changes.
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