[Biologic psychiatric research and psychiatric pharmacotherapy. Critical remarks on methods (author's transl)]

To guard satisfactorily against the discrepancy between positive experience in the field of pharmacopsychiatry and negative results in the possibility, therapeutic success or other findings of biologic psychiatric research requires a critical analysis of methods. It is concluded with a catalog of demands in the field of evaluation research. Analyses of individual cases and supporting experimental psychopathological research occupy an important role in this. Finally the obstacles to gaining knowledge in biologic psychiatric research are discussed and, deduced from this, the possible application of a research concept of Herrmann is also proposed for our specialty which would create the principles for a theoretical pluralism.