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Hyperthyroidism and polycythemia vera with chronic urticaria and angioedema
Annals of Allergy
|May 1, 1981
Summary
Chronic urticaria patients may have underlying hyperthyroidism or polycythemia vera. Further investigation is recommended to explore these potential associations in chronic hives cases.
Area of Science:
- Dermatology
- Endocrinology
- Hematology
Background:
- Chronic urticaria is a common dermatological condition.
- The etiology of chronic urticaria is often idiopathic.
- Potential systemic associations require further investigation.
Purpose of the Study:
- To investigate the prevalence of hyperthyroidism and polycythemia vera in patients with chronic urticaria.
- To explore potential causal relationships between these conditions.
Main Methods:
- Retrospective analysis of 154 chronic urticaria patients.
- Clinical evaluation for hyperthyroidism and polycythemia vera.
- Laboratory investigations including serum IgE, immune complex quantitation, and complement levels.
- Skin biopsies were performed.
Main Results:
- Six out of 154 patients (3.9%) presented with concomitant hyperthyroidism.
- Four out of 154 patients (2.6%) presented with concomitant polycythemia vera.
- Investigations failed to establish a direct causal link between chronic urticaria and these conditions.
Conclusions:
- Hyperthyroidism and polycythemia vera are potential comorbidities in patients with chronic urticaria.
- These conditions should be considered in the differential diagnosis of unexplained chronic urticaria.
- Further research may elucidate the nature of this association.