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Convulsions in the first three years of life
Insights
This study found that 6.2% of infants experienced convulsions in their first three years. Fever-associated convulsions were most common, followed by breath-holding attacks and idiopathic seizures.
Area of Science:
- Pediatrics
- Neurology
- Epidemiology
Background:
- Childhood convulsions are a significant concern for parents and healthcare providers.
- Understanding the incidence and types of convulsions in early childhood is crucial for diagnosis and management.
Purpose of the Study:
- To determine the incidence and etiology of convulsions in the first three years of life in a prospective cohort of Australian infants.
- To identify associated factors and compare pregnancy and birth data with a control group.
Main Methods:
- Prospective study of 5803 consecutive newborn infants.
- Follow-up for the first three years of life, with 90.9% retention rate.
- Classification of convulsion types including fever-associated, breath-holding, idiopathic, neonatal, and mixed aetiology.
Main Results:
- An overall incidence of 61.7 per 1000 infants experienced convulsions.
- Fever-associated convulsions occurred in 39.9 per 1000, breath-holding in 8.1 per 1000, and idiopathic in 8.2 per 1000.
- Neonatal and mixed aetiology convulsions were less common, at 2.8 per 1000 and 2.7 per 1000, respectively.
Conclusions:
- Convulsions are relatively common in early childhood, with fever-related seizures being the most frequent type.
- The study provides valuable epidemiological data on childhood convulsions, aiding in understanding their prevalence and causes.
- Further research into specific risk factors and long-term outcomes is warranted.
Abstract:
A prospective study of convulsions in 5803 consecutive newborn infants from an Australian city is described; 535 children were lost to study, leaving 90.9% of the original sample. Of the remaining 5268, 325 had at least one convulsive episode during the first three years of life--an incidence of 61.7 per thousand. Convulsions following breath-holding attacks were experienced by 8.1 per thousand, while a further 4.0 per thousand had simple breath-holding attacks associated with transient loss of consciousness, but no convulsion. Convulsions associated with fever were experienced by 39.9 per thousand. In addition, 8.2 per thousand had idiopathic convulsions, 2.8 per thousand had neonatal convulsions and 2.7 per thousand had convulsions of mixed aetiology. Factors relating to the convulsion are described in detail. Pregnancy and birth data are compared with those of a control group taken from the study.
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