Studies on polyspermia

Thirty-one couples in whom the only apparent abnormality was polyspermia in the male partner were studied in light of a suggested new definition of polyspermia. The rate of infertility was 22.5% versus 17.6% in a control group of couples with no apparent abnormalities; the difference was not statistically significant. The spontaneous abortion rate was 25.5% versus 9.7% in the controls (P less than 0.05). Semen analysis of the men showed signifcantly low fructose levels and high percentages of necrospermia and agglutination compared to controls. Various hypotheses for the etiology of polyspermia are discussed.