[Changes in the synovial membrane and the joint cartilage after treatment with osmic acid (author's transl)]

Effect of osmic acid given into the rat knee in different concentrations was studied. Both the 0,5% and the 1% concentration of osmic acid were found to produce necrosis and later regeneration of the synovial membrane. A partial necrosis of the fibrous cartilage and degenerative changes on the hyaline cartilage were observed too. Changes of the hyaline cartilage could not be assessed with certainty in their present study and further experiments are to be planned to detect them.