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Lactobacilli do not cause frequency and dysuria syndrome.

W Brumfitt, J M Hamilton-Miller, H Ludlam

Lancet (London, England)

|August 22, 1981

Summary

Lactobacilli and other vaginal bacteria are common in urine samples from healthy women and those with urinary symptoms. These bacteria are typically commensals or contaminants, not indicators of infection.

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Area of Science:

Microbiology
Urology
Gynecology

Background:

The vaginal microbiota plays a crucial role in maintaining urogenital health.
Lactobacilli are dominant bacteria in the healthy vaginal flora.
Understanding the presence of vaginal bacteria in urine is important for diagnosing urinary tract infections.

Purpose of the Study:

To investigate the prevalence and significance of lactobacilli and other fastidious bacteria in mid-stream urine (MSU) samples.
To determine if these bacteria represent normal flora or potential contaminants in healthy women and those with urinary symptoms.

Main Methods:

Urine culture of MSU samples from 142 healthy women and 26 women with dysuria/frequency.
Identification of lactobacilli and other fastidious bacteria (anaerobes, CO2-requiring).
Quantification of bacterial counts and comparison between groups.

Main Results:

Lactobacilli were frequently isolated from healthy women's urine (≥10^4/ml in 34.8%, ≥10^5/ml in 20.2%).
Anaerobic gram-positive cocci were also commonly found, consistent with vaginal flora.
Similar bacterial flora and counts were observed in women with urinary symptoms but no conventional pathogens.

Conclusions:

The presence of lactobacilli and vaginal commensals in urine samples is common and likely represents contamination or normal flora.
These findings suggest that lactobacilli in urine, in the absence of pyuria or conventional pathogens, do not necessarily indicate a urinary tract infection.

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