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Benzodiazepine dependence: a general practice survey.

A Khan, A R Hornblow, J W Walshe

    The New Zealand Medical Journal
    |July 8, 1981
    PubMed
    Summary
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    Benzodiazepine dependence is a significant concern in general practice, with many patients using higher doses than initially prescribed. This highlights the need for careful monitoring and management of these medications.

    Area of Science:

    • Pharmacology
    • General Practice
    • Public Health

    Background:

    • Benzodiazepines are commonly prescribed in general practice.
    • Concerns exist regarding their long-term use and dependence potential.
    • Understanding usage patterns is crucial for patient safety.

    Purpose of the Study:

    • To evaluate the dependence potential of benzodiazepines in a general practice setting.
    • To identify patient demographics and characteristics associated with benzodiazepine use.
    • To assess current dosage trends and reported withdrawal symptoms.

    Main Methods:

    • Cross-sectional study of 1079 general practice patients.
    • Analysis of benzodiazepine usage, duration, and dosage.
    • Interviews with a subset of 40 benzodiazepine users.

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    Main Results:

    • 8.1% of patients (87/1079) were current benzodiazepine users.
    • Users were predominantly middle-aged to elderly females with chronic illnesses.
    • 39% of users were on higher doses than initially prescribed; 17% reported withdrawal symptoms.

    Conclusions:

    • Benzodiazepine dependence is prevalent in general practice.
    • Long-term use, dose escalation, and withdrawal phenomena are significant issues.
    • Benzodiazepines may be replacing barbiturates, necessitating updated prescribing guidelines.