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Use of reflection contrast microscopy in the analysis of cellular motility
Virchows Archiv. B, Cell Pathology Including Molecular Pathology
|January 1, 1981
Abstract:
Recognition and determination of the following activities of living cancer cells on glass substrates can be greatly facilitated by the use of reflection contrast microscopy: 1. stationary versus translocative motility, 2. migration over/under other cells, 3. actual locomotory activity of cells with a polarized shape usually associated with this type of motility. In addition, reflection contrast is useful for recognizing the presence of fibroblasts in cancer cell populations.