[Parameters of bradykinin interaction with cardiovascular system receptors]

The equation describing kinetics of interaction between bradykinin and cardiovascular receptors resembles the equations describing depressive adrenergic and some cholinergic reactions in dogs, rabbits and white rats. In this study of bradykinin receptor state, in order to describe quantitatively hypotensive action of different bradykinin doses on interaction of this peptide with receptors, bradykinin had to be injected intraaortally. The data obtained revealed that the greatest efficiency of kininergic reaction occurred in dogs whereas the least--in white rats.