Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Zinc and gene expression.

B L Vallee, K H Falchuk

    Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
    |August 14, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Zinc is essential for cellular growth and development, impacting gene activation and repression. Further research is needed to understand its precise mechanisms in cell metabolism.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [36] Reactions with N-ethylmaleimide and p-mercuribenzoate.

    Methods in enzymology·2012
    Same author

    [41] acetylation.

    Methods in enzymology·2012
    Same author

    [42] o-acetyltyrosine.

    Methods in enzymology·2012
    Same author

    [44] Nitration with tetranitromethane.

    Methods in enzymology·2012
    Same author

    [45] Diazonium salts as specific reagents and probes of protein conformation.

    Methods in enzymology·2012
    Same author

    Scleredema: a systemic disease.

    The New England journal of medicine·2010

    Area of Science:

    • Biochemistry
    • Molecular Biology
    • Cell Biology

    Background:

    • Zinc is a vital cofactor for over 120 enzymes.
    • Zinc is essential for normal cellular growth, development, and differentiation.
    • The precise mechanisms of zinc's cellular functions remain largely unknown.

    Purpose of the Study:

    • To investigate the role of zinc in cellular processes.
    • To elucidate the molecular mechanisms by which zinc exerts its effects.
    • To explore zinc's influence on gene regulation.

    Main Methods:

    • Studies were conducted on the phytid E. gracilis.
    • Analysis focused on the impact of zinc on transcription and translation.
    • Investigated the metabolism of RNA polymerases, mRNA, and proteins.

    Related Experiment Videos

    Main Results:

    • Zinc was found to be critical for transcription and translation processes.
    • Zinc affects the metabolism of RNA polymerases, mRNA, and proteins, including histones and arginine-rich peptides.
    • Observed effects suggest a fundamental role in gene regulation.

    Conclusions:

    • Zinc plays a critical role in regulating gene activation and/or repression.
    • The findings suggest zinc has pervasive effects on overall cell metabolism.
    • Further research is warranted to fully understand zinc's molecular functions.