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[Collagenosis nephropathies].

L Callís

    Anales Espanoles De Pediatria
    |July 1, 1981
    PubMed
    Summary

    This review details clinical experiences with Polyarteritis Nodosa (PAN), Lupus Nephritis, and renal Amyloidosis. It highlights diverse presentations and outcomes, including hypertension and varying responses to treatment in these kidney diseases.

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    Area of Science:

    • Nephrology
    • Rheumatology
    • Internal Medicine

    Context:

    • This study reviews clinical case experiences with three distinct renal conditions: Polyarteritis Nodosa (PAN), Lupus Nephritis, and renal Amyloidosis.
    • The review encompasses patients presenting with arterial hypertension, nephrotic syndrome, and specific pathological findings on kidney biopsy.

    Purpose:

    • To present and analyze the authors' clinical experience with patients diagnosed with PAN, Lupus Nephritis, and renal Amyloidosis.
    • To illustrate the varied clinical manifestations, diagnostic approaches, and treatment outcomes associated with these renal pathologies.

    Summary:

    • Two patients with Polyarteritis Nodosa (PAN) experienced arterial hypertension; one with macroscopic PAN had aneurysms in cerebral and renal arteries, while microscopic PAN responded well to corticotherapy over three years.
    • Four patients with Lupus Nephritis presented with nephrotic syndrome and arterial hypertension; kidney biopsies revealed membranoproliferative glomerulonephritis in two and extramembranous glomerulonephritis in one.
    • Seven patients with renal Amyloidosis were analyzed, with causes including rheumatoid arthritis (four cases), mucoviscidosis (two cases), and recurrent Mediterranean fever (one case).

    Impact:

    • Provides insights into the heterogeneous clinical spectrum of rare renal diseases.
    • Offers practical examples of diagnostic challenges and therapeutic responses in managing complex kidney conditions.
    • Contributes to the understanding of disease progression and patient outcomes in Polyarteritis Nodosa, Lupus Nephritis, and renal Amyloidosis.

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