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Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
09:02

Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver

Published on: July 31, 2016

Treatment of pyogenic liver abscesses by percutaneous needle aspiration

L A Berger, D R Osborne

    Lancet (London, England)
    |January 16, 1982
    PubMed

    Insights

    Percutaneous aspiration guided by ultrasound is an effective and safe treatment for pyogenic liver abscesses. This minimally invasive procedure led to abscess healing in all patients, with no reported mortality.

    Area of Science:

    • Hepatology
    • Infectious Diseases
    • Interventional Radiology

    Background:

    • Pyogenic liver abscesses are serious infections requiring prompt diagnosis and effective treatment.
    • Traditional treatment methods may involve open surgery, carrying significant risks.
    • Ultrasound has become a key imaging modality for diagnosing liver abscesses.

    Purpose of the Study:

    • To evaluate the efficacy and safety of ultrasound-guided percutaneous aspiration for treating pyogenic liver abscesses.
    • To determine the role of anaerobic organisms in pyogenic liver abscesses.
    • To establish percutaneous aspiration as a primary treatment modality.

    Main Methods:

    • Fifteen patients with pyogenic liver abscesses underwent ultrasound-guided percutaneous aspiration.
    • Pus samples were immediately cultured for aerobic and anaerobic bacteria.
    • Appropriate antibiotic therapy was initiated based on culture results.

    Main Results:

    • All fifteen patients showed clinical improvement following aspiration.
    • Complete abscess healing was achieved in all cases, with only two requiring repeat aspirations.
    • No treatment-related complications or mortality were observed.
    • Anaerobic organisms were identified in nine of the cases.

    Conclusions:

    • Ultrasound-guided percutaneous aspiration is a simple, safe, and highly effective treatment for pyogenic liver abscesses.
    • This technique offers a minimally invasive alternative to surgery.
    • Prompt diagnosis and targeted antibiotic therapy, guided by aspiration cultures, are crucial for successful outcomes.

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