Related Experiment Videos
Cardiovascular effects of sufentanil anesthesia
Anesthesia and Analgesia
|February 1, 1982
Summary
Sufentanil, a potent synthetic opiate analgesic, demonstrated good cardiovascular stability in adult patients undergoing cardiac surgery when used as a complete anesthetic. This anesthetic technique warrants further investigation for its efficacy and safety.
Area of Science:
- Anesthesiology
- Cardiovascular Pharmacology
Background:
- Sufentanil is a potent synthetic opiate analgesic.
- Its cardiovascular effects in cardiac surgery patients require evaluation.
Purpose of the Study:
- To evaluate the cardiovascular effects of sufentanil (15 µg/kg) as a complete anesthetic agent.
- To assess the safety and efficacy of sufentanil-air/O2 anesthesia in adult cardiac surgery.
Main Methods:
- Forty adult patients undergoing elective or emergency cardiac surgery were administered sufentanil (15 µg/kg) with an air/O2 anesthetic mixture.
- Cardiovascular parameters including blood pressure and peripheral resistance were monitored.
Main Results:
- A decrease in systolic pressure was observed 5 minutes post-induction.
- Systolic and mean blood pressures, along with peripheral resistance, decreased before incision.
- Hypertension occurred in 16 patients during sternotomy, while 2 experienced hypotension upon induction.
Conclusions:
- Sufentanil anesthesia appears to provide adequate cardiovascular stability for cardiac surgery.
- This anesthetic approach is a viable option meriting additional research and clinical trials.