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Impaired central error-correcting behavior in schizophrenia.

R C Malenka, R W Angel, B Hampton

Archives of General Psychiatry

|January 1, 1982

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Schizophrenic patients struggle to correct movement errors internally, unlike healthy individuals or alcoholics. This indicates a deficit in monitoring motor behavior using self-generated cues.

Area of Science:

Neuroscience
Cognitive Psychology
Psychiatry

Background:

Normal subjects can correct movement errors without external feedback.
This self-correction ability may be compromised in schizophrenia.

Purpose of the Study:

To investigate the ability to correct movement errors without exteroceptive signals in schizophrenics, alcoholics, and normal subjects.
To determine if schizophrenia impairs internal monitoring of motor behavior.

Main Methods:

A step-function tracking task was used, preventing exteroceptive signal reliance.
Participants included 12 normal subjects, 12 alcoholics, and 14 schizophrenics.

Main Results:

Schizophrenics had a lower probability (.38) of correcting errors without external cues compared to normal subjects (.70) and alcoholics (.75).

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No group differences were found in initiating correct responses.

Conclusions:

Schizophrenia is associated with a deficiency in self-monitoring of ongoing motor behavior.
Internal, self-generated cues are crucial for motor error correction, and this mechanism appears impaired in schizophrenia.