[Effect of obzidan on cerebral blood flow in acute cerebral ischemia]

The effect of obsidan on the local cerebral circulation was studied in cats with normal brain circulation and under acute cerebral ischemia. It was demonstrated that obsidan (0.2 mg/kg) increased local cerebral circulation, while on being given in a dose of 1 mg/kg it lowered it in cats with normal brain circulation. In animals with stroke (both on the side with normal circulation and on the side of cerebral ischemia) obsidan (0.2 mg/kg) significantly decreased the local cerebral circulation and destroyed autoregulation of the brain circulation.