Stimulated release of 3H-glycine from retina

The release of 3H-glycine was studied from rabbit retinas. Kainic acid (10(-5) M), a glutamate agonist, evoked prompt CA2+-dependent increased release of 3H-glycine. However, nuciferine (10(-4) M) could not suppress the effect of kainic acid. The effect of glutamic acid (10(-5) M) was significantly reduced in the presence of nuciferine (10(-4) M). The GABA analogues, muscimol and THIP, had no effect on the release of 3H-glycine. Aspartate and cystic acid were also without effect.