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[Isolated renal involvement in periarteritis nodosa]
Schweizerische Medizinische Wochenschrift
|January 16, 1982
Summary
Periarteritis nodosa (PAN) can present unusually with acute renal failure and high blood pressure. Renal angiography is key for diagnosing PAN in such cases, guiding treatment with immunosuppressants and steroids.
Area of Science:
- Nephrology
- Rheumatology
- Vascular Medicine
Background:
- Periarteritis nodosa (PAN) frequently affects kidneys (70%) but typically involves multiple organs.
- Unusual initial presentations of PAN with acute renal failure (ARF) and high blood pressure (HBP) are rare.
Observation:
- Two patients presented with ARF and HBP without signs of other organ involvement.
- Diagnosis of PAN was confirmed by identifying microaneurysms on renal angiograms.
Findings:
- Combined immunosuppressive and steroid therapy controlled HBP in both patients.
- One patient experienced improved renal function following treatment.
Implications:
- ARF and HBP without other organ involvement can indicate PAN.
- Renal angiography is crucial for diagnosing PAN in this clinical context.
- Prompt diagnosis and treatment are essential for managing PAN-related renal complications.