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Abstract:
Nonlymphangiophlebitic hypodermatitis includes acute, subacute and chronic afflictions. The first are primarily expressed by erythema nodosum, which can be triggered by many factors and is characterized microscopically by the presence in the interlobular septa of lymphocytes, histiocytes and polynuclears. Subacute and chronic hypodermic inflammation have different microscopic substrata. Erythema induratum is a form of cutaneous tuberculosis; its nodules result from the presence of tuberculous infiltrates in the fat lobules. The lesions of nodular vasculitis are the clinical expression of an affliction of the hypodermic vessels, and of a migratory thrombophlebitis, betraying the subjacent venous alterations. The different inflammatory lesions must be distinguished from panniculitis, which is marked by a preferential attack of the adipose tissue. Gummas are subcutaneous nodules which evolve towards necrosis and which can be caused by syphilis, tuberculosis or deep fungal infections.