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Updated: Aug 18, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
[Oestriol effect upon prolactinaemia in postmenopausal women (author's transl)]
Abstract:
Six postmenopausal women were treated at two ocasions with an oral dose of, respectively, 2 mg and 6 mg oestriol per day for 14 days; at least one month interval separated the two treatment periods. Blood was collected for prolactin measurement (homologous human radioimmunoassay) every other day during each treatment period as well as during a 14 days control period in the same subjects. Mean prolactin level during oestriol administration, regardless of the dose, was statistically not significantly different from that observed during the control period.
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