Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Alpha receptor blocking and cardial insufficiency].

W Klein

    Wiener Medizinische Wochenschrift (1946)
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Prazosin, an alpha receptor blocker, effectively treats severe congestive heart failure by improving clinical and hemodynamic measures. This vasodilator medication offers significant benefits without adverse counterregulatory effects after four weeks of treatment.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Efficiency and safety of ACE-inhibiting imidapril in patients with essential hypertension].

    Acta medica Austriaca·2002
    Same author

    Movement of metolachlor and terbuthylazine in core and packed soil columns.

    Chemosphere·2002
    Same author

    Spinodals, scaling, and ergodicity in a threshold model with long-range stress transfer.

    Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics·2002
    Same author

    Self-organization in leaky threshold systems: the influence of near-mean field dynamics and its implications for earthquakes, neurobiology, and forecasting.

    Proceedings of the National Academy of Sciences of the United States of America·2002
    Same author

    Nucleation in systems with elastic forces.

    Physical review letters·2002
    Same author

    A polymorphism in the CD14 gene is associated with Crohn disease.

    Scandinavian journal of gastroenterology·2002
    Same journal

    Necrotizing fasciitis of the thigh-a devastating sign of intestinal perforation.

    Wiener medizinische Wochenschrift (1946)·2026
    Same journal

    Regenerative therapies in rehabilitation with interfaces with occupational medicine, geriatrics, and oncology: the example of extracorporeal shock wave therapy.

    Wiener medizinische Wochenschrift (1946)·2026
    Same journal

    Cerebral toxoplasmosis in patients with peripheral B-cell lymphoma : A case series and a literature review.

    Wiener medizinische Wochenschrift (1946)·2026
    Same journal

    Post-pandemic rebound of rotavirus and adenovirus in pediatric gastroenteritis: a 6-year antigen-based surveillance study from Turkey.

    Wiener medizinische Wochenschrift (1946)·2026
    Same journal

    Neuroaxis involvement in Chikungunya virus infection: a retrospective case series.

    Wiener medizinische Wochenschrift (1946)·2026
    Same journal

    A complicated case of a spinal Scedosporium apiospermum infection with a favorable outcome-case report.

    Wiener medizinische Wochenschrift (1946)·2026
    See all related articles

    Area of Science:

    • Cardiology
    • Pharmacology

    Context:

    • Severe left ventricular failure often requires advanced treatment strategies.
    • Alpha receptor blockers are known potent vasodilators.

    Purpose:

    • To evaluate the efficacy of Prazosin in patients with severe congestive heart failure refractory to standard treatments.
    • To assess the clinical and hemodynamic effects of Prazosin administration.

    Summary:

    • Eleven patients with congestive heart failure received 9 mg of Prazosin daily for four weeks.
    • Significant improvements were observed in clinical status and hemodynamic parameters, including reduced cardiothoracic ratio and peripheral vascular resistance, alongside increased cardiac output, stroke volume, and stroke work.
    • No significant changes were noted in heart rate or plasma catecholamines, indicating a lack of counterregulation.

    Related Experiment Videos

    Impact:

    • Prazosin demonstrates a beneficial effect in managing severe congestive heart failure.
    • The study highlights Prazosin's potential as a therapeutic option for refractory heart failure.
    • Results suggest Prazosin provides sustained hemodynamic improvement without significant adverse effects.