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Prolactin secretion response to TRH stimulation in acute and chronic schizophrenic patients under neuroleptic
International Pharmacopsychiatry
|January 1, 1982
Abstract:
Prolactin (PRL) serum levels in a group of patients with acute schizophrenia (AS) and in a group of patients with chronic schizophrenia (CS) have been investigated in order to differentiate the dopaminergic sensitivity in response to chlorpromazine (CPZ) treatment. AS patients show both a greater dopaminergic sensitivity to CPZ and a stronger response in PRL secretion to TRH stimulation after a 14-day CPZ treatment.