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The case for global measles eradication.

D R Hopkins, A R Hinman, J P Koplan

    Lancet (London, England)
    |June 19, 1982
    PubMed
    Summary
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    Global measles eradication is achievable and desirable due to the disease's widespread impact and the availability of effective vaccines. Eradicating measles would save lives and reduce healthcare costs worldwide.

    Area of Science:

    • Public Health
    • Infectious Diseases
    • Vaccinology

    Background:

    • Measles is a highly prevalent infectious disease causing significant mortality, particularly in developing nations.
    • The disease affects a large pediatric population, leading to severe complications and substantial annual deaths.
    • Ongoing global efforts address measles due to its universal occurrence and severe health burden.

    Purpose of the Study:

    • To assess the feasibility and desirability of a global measles eradication program.
    • To highlight the potential benefits of measles eradication, including saving lives and reducing healthcare expenditures.
    • To provide evidence supporting the initiation of a comprehensive measles eradication strategy.

    Main Methods:

    • Review of historical disease eradication successes, specifically smallpox eradication.

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  • Assessment of the characteristics of the measles vaccine, including stability, cost, and efficacy.
  • Analysis of documented instances of measles transmission interruption in various regions.
  • Main Results:

    • Measles eradication is deemed feasible, supported by precedents like smallpox eradication.
    • The availability of an effective, affordable, and heat-stable measles vaccine enhances eradication prospects.
    • Successful interruption of measles transmission in localized areas demonstrates the potential for global success.

    Conclusions:

    • Global measles eradication is a desirable and attainable public health goal.
    • Achieving measles eradication will prevent millions of deaths annually, especially among children.
    • Eradication offers significant economic benefits by eliminating costs associated with measles treatment, vaccination, and surveillance.