Related Experiment Video
Updated: Aug 14, 2026

T Cells Capture Bacteria by Transinfection from Dendritic Cells
Published on: January 13, 2016
Role of T lymphocytes in Rickettsia conorii infection
Abstract:
Adoptive transfer of T lymphocytes harvested from spleen of Rickettsia conorii-infected DBA/2 mice to intact and cyclophosphamide- (CPA-) pretreated syngeneic mice protected the latter from lethal infection caused by R, conorii. Protection from infection was not observed in recipient mice given immune serum or B lymphocytes and macrophages from the spleens of convalescent mice. The protective effect was most pronounced after intravenous transfer of lymphocytes obtained from donor mice on day 14 post infection. Lethal infection was not prevented by transfer of lymphocytes harvested on day 50 p. i., although at this interval the donor mice were still resistant to reinfection with F. conorii.
More Related Videos
Related Concept Videos
Cell-mediated Immune Responses
Intracellular Movement of Viruses and Bacteria
T Cell Activation and Clonal Selection
Naive T cells that have not yet encountered an antigen express two primary CD...
T Cell Types and Functions
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Rocky Mountain Spotted Fever

