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The activity of lysyl oxidase in experimental hepatic fibrosis
Hepato-Gastroenterology
|October 1, 1981
Abstract:
Hepatic collagen synthesis was studied during progressive fibrosis induced by carbon tetrachloride in male Sprague-Dawley rats by determination of lysyl oxidase activity, hydroxyproline levels and morphological assessment. The activity of lysyl oxidase was increased significantly when fibrosis became apparent histologically.