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A new mathematical approach to describe transmural gastric potential difference changes (great moments in
Arzneimittel-Forschung
|January 1, 1982
Abstract:
The time moments of a gastric potential difference (PD) vs. time curve may be used to determine its time characteristics (mean time, and variance around the mean time). In addition, the PD moments determine its PD characteristics (mean PD, and variance around the mean PD). Such characteristics are useful in comparing the irritation on the gastric mucosa caused by different drugs and dosages and in evaluating the histamine blocking effect of compounds.