Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Beta-adrenergic blockade in clinical practice.

W H Frishman

    Hospital Practice (Office Ed.)
    |September 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Beta-blocking agents, despite similar pharmacologic effects, differ in pharmacokinetics, impacting individual patient treatment. This review examines their efficacy and mechanisms in cardiovascular and noncardiovascular conditions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    AIDS and the heart: Clinicopathologic assessment.

    Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
    Same author

    ACE inhibitors and the arterial wall. Introduction.

    Postgraduate medicine·2009
    Same author

    Pathophysiology and medical management of systemic hypertension and pre-eclampsia in pregnancy.

    Minerva medica·2006
    Same author

    Antiplatelet therapy: glycoprotein IIb/IIIa receptor antagonists.

    Drugs of today (Barcelona, Spain : 1998)·2003
    Same author

    Alcohol as a cardioprotective agent.

    Heart disease (Hagerstown, Md.)·2002
    Same author

    Cardiopulmonary resuscitation 2000.

    Heart disease (Hagerstown, Md.)·2002
    Same journal

    Oral contraceptives: an update.

    Hospital practice (Office ed.)·1995
    Same journal

    Progress in the immunogenetics of rheumatoid arthritis.

    Hospital practice (Office ed.)·1995
    Same journal

    An asymptomatic lung nodule in an elderly woman with joint pain.

    Hospital practice (Office ed.)·1995
    Same journal

    Defusing status epilepticus.

    Hospital practice (Office ed.)·1995
    Same journal

    Persistent fever and flank discomfort in a young woman.

    Hospital practice (Office ed.)·1995
    Same journal

    New thoughts on attention-deficit/hyperactivity disorder.

    Hospital practice (Office ed.)·1995
    See all related articles

    Area of Science:

    • Pharmacology
    • Clinical Medicine
    • Drug Metabolism

    Background:

    • Beta-blocking agents share core pharmacologic actions.
    • Significant inter-agent pharmacokinetic variability exists.
    • Pharmacokinetics influence clinical utility and patient response.

    Purpose of the Study:

    • To review the efficacy of beta-blocking agents across various disorders.
    • To discuss the mechanisms of action in different clinical contexts.
    • To highlight the importance of pharmacokinetic properties in therapeutic selection.

    Main Methods:

    • Literature review of beta-blocking agents.
    • Analysis of pharmacokinetic and pharmacodynamic data.
    • Synthesis of clinical evidence for efficacy in diverse conditions.

    Related Experiment Videos

    Main Results:

    • Beta blockers demonstrate efficacy in numerous cardiovascular and noncardiovascular conditions.
    • Pharmacokinetic differences (e.g., absorption, metabolism, elimination) are substantial.
    • Mechanisms of action vary depending on the specific agent and disease context.

    Conclusions:

    • Individualized selection of beta blockers is crucial due to pharmacokinetic differences.
    • Understanding drug disposition is key to optimizing therapeutic outcomes.
    • Beta blockers remain vital therapeutic agents for a wide spectrum of diseases.