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Impaired TSH response to TRH after intravenous ranitidine in man
Abstract:
Ranitidine, given by i.v. infusion, decreased TSH response to TRH in 7 subjects. This effect, completely different from that obtained with cimetidine, suggests that the action of ranitidine is likely to be independent of H2-receptor blockade and rather may be related to the cholinergic-like effect of this drug.