Protecting poor metabolizers, a group at high risk of adverse drug reactions

Metabolomics reveals that aldose reductase activity due to AKR1B10 is upregulated in hepatitis C virus infection.

Journal of viral hepatitis·2014

Miotic action of tramadol is determined by CYP2D6 genotype.

Physiological research·2006

Christmas gingerbread (Lebkuchen) and Christmas cheer--review of the potential role of mood elevating amphetamine-like compounds formed in vivo and in furno.

Prague medical report·2005

Early glucose and methylene blue are effective against unripe ackee apple (Blighia sapida) poisoning in mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2004

Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients.

The pharmacogenomics journal·2003

The CYP2D6 humanized mouse: effect of the human CYP2D6 transgene and HNF4alpha on the disposition of debrisoquine in the mouse.

Molecular pharmacology·2001

8 weeks versus 12 weeks of sofosbuvir-velpatasvir for treatment-naive, non-cirrhotic, chronic hepatitis C (RESOLVE): a multicentre, open-label, non-inferiority, randomised controlled trial in India.

Lancet (London, England)·2026

Cardiovascular safety of orforglipron versus insulin glargine in adults with type 2 diabetes at increased cardiovascular risk (ACHIEVE-4): a phase 3, event-driven, randomised, open-label, non-inferiority, active comparator trial.

Lancet (London, England)·2026

A trembling detour to the diagnosis of encephalitis: a neuroborreliosis case report.

Lancet (London, England)·2026

Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a double-blind, parallel-group, randomised, placebo-controlled, phase 3 trial.

Lancet (London, England)·2026

Efficacy and safety of garetosmab, an activin A-blocking antibody, in fibrodysplasia ossificans progressiva (OPTIMA): a randomised, double-blind, placebo-controlled, phase 3 trial.

Lancet (London, England)·2026

Radiotherapy versus observation following surgical resection of WHO grade 2 atypical meningioma (ROAM/EORTC-1308): an international, multicentre, open-label, phase 3, randomised controlled trial.

Lancet (London, England)·2026

Precision medicine requires precision prescribing: rethinking antiseizure medication regulation in Europe.

Current medical research and opinion·2026

Pharmacy professionals' knowledge, attitudes, and behaviours regarding antibiotic use and antimicrobial resistance in Oman.

Journal of pharmaceutical policy and practice·2026

Decitabine modulates dopamine agonist sensitivity in gh3 rat pituitary tumor cells via Trim7.

Frontiers in endocrinology·2026

Predictors of treatment response to semaglutide for weight management.

Frontiers in endocrinology·2026

Exploratory cluster analysis of self-reported adverse events associated with antidepressants using Gower distance and partitioning around medoids: a single-center cross-sectional study.

Frontiers in psychiatry·2026

Conformation- and Compound-Dependence of Ribose/2'-Deoxyribose Retention Patterns in Pyrimidine-Nucleoside Phosphorylase from Bacillus subtilis: A Four-Structure Molecular Dynamics Study.

ACS omega·2026

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Protecting poor metabolizers, a group at high risk of adverse drug reactions

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Metabolomics reveals that aldose reductase activity due to AKR1B10 is upregulated in hepatitis C virus infection.

Miotic action of tramadol is determined by CYP2D6 genotype.

Christmas gingerbread (Lebkuchen) and Christmas cheer--review of the potential role of mood elevating amphetamine-like compounds formed in vivo and in furno.

Early glucose and methylene blue are effective against unripe ackee apple (Blighia sapida) poisoning in mice.

Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients.

The CYP2D6 humanized mouse: effect of the human CYP2D6 transgene and HNF4alpha on the disposition of debrisoquine in the mouse.

8 weeks versus 12 weeks of sofosbuvir-velpatasvir for treatment-naive, non-cirrhotic, chronic hepatitis C (RESOLVE): a multicentre, open-label, non-inferiority, randomised controlled trial in India.

Cardiovascular safety of orforglipron versus insulin glargine in adults with type 2 diabetes at increased cardiovascular risk (ACHIEVE-4): a phase 3, event-driven, randomised, open-label, non-inferiority, active comparator trial.

A trembling detour to the diagnosis of encephalitis: a neuroborreliosis case report.

Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a double-blind, parallel-group, randomised, placebo-controlled, phase 3 trial.

Efficacy and safety of garetosmab, an activin A-blocking antibody, in fibrodysplasia ossificans progressiva (OPTIMA): a randomised, double-blind, placebo-controlled, phase 3 trial.

Radiotherapy versus observation following surgical resection of WHO grade 2 atypical meningioma (ROAM/EORTC-1308): an international, multicentre, open-label, phase 3, randomised controlled trial.

Precision medicine requires precision prescribing: rethinking antiseizure medication regulation in Europe.

Pharmacy professionals' knowledge, attitudes, and behaviours regarding antibiotic use and antimicrobial resistance in Oman.

Decitabine modulates dopamine agonist sensitivity in gh3 rat pituitary tumor cells via Trim7.

Predictors of treatment response to semaglutide for weight management.

Exploratory cluster analysis of self-reported adverse events associated with antidepressants using Gower distance and partitioning around medoids: a single-center cross-sectional study.

Conformation- and Compound-Dependence of Ribose/2'-Deoxyribose Retention Patterns in Pyrimidine-Nucleoside Phosphorylase from Bacillus subtilis: A Four-Structure Molecular Dynamics Study.

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Protecting poor metabolizers, a group at high risk of adverse drug reactions

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