[Secondary diencephalic dysfunctions in patients with sympathoganglionitis and their pathogenetic treatment]

Novel concepts of both the pathogenesis of secondary trunko-hypothalamic dysfunctions ("repercussive diencephaleses") associated with sympathoganglionites and their pathogenetic therapy are offered. They are based on new fundamental data concerning the physiology of vegetative ganglia, as well as on the findings of the clinical and electroencephalographic examinations, and the results of treatment of 67 patients with cervical sympathoganglionites. The suggested method of pathogenetic therapy consists of pharmacologically-induced blocking of the pathological afferent impulsation from the affected sympathetic ganglion; which is achieved by mild solutions of ganglioblockers administered into the ganglion; which is achieved by mild solutions of ganglioblockers administered into the ganglion by graded electrophoresis. Most of the patients showed a good therapeutic response. Data on the differential use of electrophoresis with either benzohexamethonium or gangleron, depending on the clinical manifestations of the disease, are presented.