Timing of ovulation for AIH with freeze-thawed, subfertile sperm: two case studies

Two couples were studied in whom the male partner had become sterile due to irradiation therapy given for advanced Hodgkin's disease. Both couples achieved conception during the first and second treatment cycle, respectively, despite obviously subfertile freeze-thawed sperm. The success is attributed to optimal timing of a single homo-insemination (AIH), which was made possible because we could detect ovulation by using currently available sophisticated methods. The importance of precise timing of ovulation for insemination and the ability to retain fertilizing capacity of young males with compromised sperm, who underwent sterilizing treatment, is discussed.