[Effect of furosemide on venous capacity in anuric or binephrectomized patients]

Several reports about an extrarenal effect of Furosemide, consisting in venodilatation and venous pooling have been published during the last years. Some authors however deny any extrarenal effect. Changes in venous capacity of the leg were measured before and after Furosemide administration in anuric and binephrectomized patients, using the technique of occlusive rheography. According to the augmented venous pooling, all patients showed a significant decrease of venous capacity after Furosemide. This effect is certainly extrarenal.