Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Which behavior does the lamprey central motor program mediate?

J Ayers, G A Carpenter, S Currie

    Science (New York, N.Y.)
    |September 23, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Reactogenicity and immunogenicity following heterologous and homologous third dose COVID-19 vaccination in UK adolescents (Com-COV3): A randomised controlled non-inferiority trial.

    The Journal of infection·2025
    Same author

    Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment.

    Physical review letters·2024
    Same author

    Crystal response measurement of the x-ray transmission crystals used by the Imaging Spectroscopy Snout at the National Ignition Facility.

    The Review of scientific instruments·2022
    Same author

    A 2-4 keV multilayer mirrored channel for the NIF Dante system.

    The Review of scientific instruments·2022
    Same author

    Sub-keV design for the National Ignition Facility's soft x-ray Opacity Spectrometer (OpSpec) and expansion plans for time-resolved measurements.

    The Review of scientific instruments·2022
    Same author

    Lawson Criterion for Ignition Exceeded in an Inertial Fusion Experiment.

    Physical review letters·2022
    Same journal

    Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

    Science (New York, N.Y.)·2026
    Same journal

    Local signals, systemic decline.

    Science (New York, N.Y.)·2026
    Same journal

    The mechanics of liver regeneration.

    Science (New York, N.Y.)·2026
    Same journal

    Computing in a memory with physics.

    Science (New York, N.Y.)·2026
    Same journal

    Retraction.

    Science (New York, N.Y.)·2026
    Same journal

    Making time.

    Science (New York, N.Y.)·2026
    See all related articles

    The isolated lamprey spinal cord generates motor neuron discharge with D-glutamic acid. However, these D-glutamate-induced movements differ from natural swimming and accurately predict undulations in spinally transected lampreys.

    Area of Science:

    • Neuroscience
    • Biophysics
    • Animal Behavior

    Background:

    • The central motor program for swimming in lampreys is typically studied using isolated spinal cord preparations.
    • D-glutamic acid is known to induce motor neuron discharge in these preparations, mimicking swimming behavior.

    Purpose of the Study:

    • To compare the undulatory movement parameters generated by D-glutamate in isolated lamprey spinal cords with those observed during natural behaviors.
    • To determine if D-glutamate-induced motor patterns accurately predict undulations in lampreys with spinal cord injuries.

    Main Methods:

    • Isolated lamprey spinal cords were bathed in 2 millimolar D-glutamic acid to induce motor neuron discharge.
    • Computer analysis of motion pictures of behaving lampreys was used to estimate undulatory movement parameters.

    Related Experiment Videos

  • D-glutamate-induced undulations were directly compared with parameters from normal swimming and spinally transected lampreys.

    • Main Results:

    • The movement parameters generated by D-glutamate were significantly different from those observed during normal lamprey swimming.
    • D-glutamate-induced undulations accurately predicted the movement patterns of spinally transected adult lampreys.

    Conclusions:

    • The motor program induced by D-glutamic acid in isolated lamprey spinal cords does not fully replicate natural swimming behavior.
    • This model provides valuable insights into spinal cord function and motor control, particularly in the context of spinal injury.