Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vascular ulcers in scleroderma.

J R Thomas, R K Winkelmann

    Archives of Dermatology
    |October 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Scleroderma patients with lower extremity ulcers and specific skin lesions may have underlying vascular disease. Early examination is crucial for diagnosing conditions like livedoid vasculitis or endarteritis obliterans.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Snake Bites-Treated by Brandy.

    The North-Western medical and surgical journal·2023
    Same author

    Temperature surpasses the effects of velocity and turbulence on swimming performance of two invasive non-native fish species.

    Royal Society open science·2021
    Same author

    Development of a core outcome set for cutaneous squamous cell carcinoma trials: identification of core domains and outcomes.

    The British journal of dermatology·2020
    Same author

    Leaf consumption by insects in three Eucalyptus forest types in Southeastern Australia and their role in short-term nutrient cycling.

    Oecologia·2017
    Same author

    Effects of nitrogen concentrations of Eucalyptus blakelyi foliage on the fecundity of Paropsis atomaria (Coleoptera: Chrysomelidae).

    Oecologia·2017
    Same author

    Effects of food quality, particularly nitrogen concentrations, of Eucalyptus blakelyi foliage on the growth of Paropsis atomaria larvae (Coleoptera: Chrysomelidae).

    Oecologia·2017

    Area of Science:

    • Dermatology
    • Rheumatology
    • Vascular Medicine

    Background:

    • Scleroderma is a chronic autoimmune disease characterized by hardening and tightening of the skin.
    • Lower extremity ulcers can be a debilitating complication in patients with scleroderma.
    • Associated skin findings like livedo reticularis and atrophie blanche may indicate underlying pathology.

    Observation:

    • Seven patients with scleroderma presented with lower extremity ulcers.
    • These patients also exhibited livedo reticularis or atrophie blanche skin lesions.
    • Associated conditions included livedoid vasculitis, periarteritis nodosa, and endarteritis obliterans.

    Findings:

    • Five patients had livedoid vasculitis, one had lupus panniculitis, and one had rheumatoid arthritis.

    Related Experiment Videos

  • Laboratory findings included elevated erythrocyte sedimentation rates (ESRs) and positive antinuclear antibody (ANA) and rheumatoid factor (RF) tests in some patients.
  • The presence of scleroderma with livedoid vasculitis or livedo reticularis and ulcers suggests potential underlying vascular disease.

    • Implications:

    • Patients with scleroderma, livedoid vasculitis, livedo reticularis, and ulcers require thorough evaluation for vascular disease.
    • Diagnosing conditions such as endarteritis obliterans is critical for appropriate management.
    • This highlights the importance of a multidisciplinary approach in managing complex scleroderma cases.