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Dyskinesias in the geriatric population.
Brain Research Bulletin
|August 1, 1983
Summary
Dyskinesias affect over 22% of geriatric patients on neuroleptics, with higher rates in males. Combined antipsychotic and antiparkinsonian drugs significantly increase abnormal movement prevalence.
Area of Science:
- Geriatric Medicine
- Neurology
- Psychopharmacology
Background:
- Dyskinesias are involuntary movements that can affect elderly patients.
- Neuroleptic medications are commonly used in geriatric care but may cause side effects.
- Understanding the prevalence and risk factors for dyskinesias in nursing home residents is crucial.
Purpose of the Study:
- To determine the prevalence of spontaneous and drug-induced dyskinesias in a UK geriatric nursing home population.
- To identify factors associated with increased risk, including neuroleptic use and polypharmacy.
Main Methods:
- A cross-sectional study involving 500 residents in British geriatric nursing homes.
- Assessment of dyskinesias using the Abnormal Involuntary Movement Scale (AIMS).
- Analysis of medication use, including neuroleptics and antiparkinsonian drugs.
Main Results:
- Overall dyskinesia prevalence was 13.2%, rising to 22.1% in patients on neuroleptics.
- Males (21.2%) had a higher prevalence than females (13.2%).
- Conjoint antipsychotic and antiparkinsonian treatment showed the highest prevalence (40.6%). Age was not a significant factor.
Conclusions:
- Neuroleptic medication significantly increases the risk of dyskinesias in geriatric patients.
- Combination therapy with antipsychotics and antiparkinsonians poses a substantial risk.
- Regular assessment for abnormal movements is essential in this vulnerable population.