[Multiple endocrine adenopathy type IIb. 15-years' observation of a case]

MEA IIb is a combination of C-cell carcinoma of the thyroid, phaeochromocytoma, multiple neuromas and a marfanoid habitus. A hyperplasia of the parathyroid cannot be found in most of the patients with this variant of Sipple's syndrome. In a 30-year-old woman, a MEA IIb could be observed over 15 years. Although primary surgery of the C-cell-carcinoma was insufficient, metastases were not found following two more surgical interventions in spite of elevated serum calcitonin. A phaeochromocytoma was not found, too. The reported case is compared with the literature.