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Related Experiment Videos

Respiratory morbidity and lung function after whooping-cough.

I D Johnston, H R Anderson, H P Lambert

    Lancet (London, England)
    |November 12, 1983
    PubMed
    Summary

    Children who had whooping cough (pertussis) did not show lasting lung problems. While they had more chest illnesses, this may have started before the whooping cough infection.

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    Area of Science:

    • Pediatric respiratory health
    • Infectious disease epidemiology

    Background:

    • Whooping cough (pertussis) is a significant childhood illness.
    • Previous studies suggest potential long-term respiratory effects of pertussis.

    Purpose of the Study:

    • To investigate the long-term respiratory health outcomes in primary-school children following whooping cough.
    • To determine if whooping cough leads to subsequent respiratory morbidity or impaired lung function.

    Main Methods:

    • A case-control study comparing 360 primary-school children with a history of whooping cough to 711 controls.
    • Assessment of past and current respiratory symptoms, physical examinations, and lung function tests.

    Main Results:

    • Children with a history of whooping cough reported more chest illnesses than controls, but this may predate the infection.
    • Increased current respiratory symptoms were observed in children with a history of whooping cough.
    • No significant differences in physical examination findings or lung function were detected between cases and controls.

    Conclusions:

    • Whooping cough, as experienced in recent UK populations, is unlikely to cause significant long-term respiratory morbidity.
    • Pertussis infection in childhood does not appear to result in impaired lung function in later childhood.

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